Status:

COMPLETED

Impact of Nasal Saline Irrigations on Viral Load in Patients With COVID-19

Lead Sponsor:

Vanderbilt University Medical Center

Conditions:

COVID 19

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Nasal saline irrigations are a safe and commonly used mechanism to treat a variety of sinonasal diseases including sinusitis, rhinitis, and upper respiratory tract infections. When used properly, thes...

Detailed Description

The novel coronavirus known as SARS-CoV-2 and the associated disease process COVID-19 (coronavirus disease 2019) was first seen in late 2019 in Wuhan, China. Over the following months, it quickly spre...

Eligibility Criteria

Inclusion

  • Patients testing positive for COVID-19 at Vanderbilt University Medical Center or VUMC-associated testing centers
  • Age of 18 years or greater
  • Patients must be planning self-quarantine after infection in the greater Nashville area within a 30-mile radius of Vanderbilt University Medical Center

Exclusion

  • Requiring hospitalization - only outpatient COVID-19 cases are eligible for the study
  • Current use of nasal saline irrigations or other intranasal medications
  • Inability to perform saline irrigations/nasal swabs in separate bathroom away from household contacts

Key Trial Info

Start Date :

May 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 16 2022

Estimated Enrollment :

88 Patients enrolled

Trial Details

Trial ID

NCT04347538

Start Date

May 1 2020

End Date

March 16 2022

Last Update

October 15 2024

Active Locations (1)

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Vanderblt University Medical Center

Nashville, Tennessee, United States, 37232