Status:
UNKNOWN
Intestinal Flora and Major Depressive Disorders
Lead Sponsor:
Beijing Chao Yang Hospital
Collaborating Sponsors:
Capital Medical University
Conditions:
Major Depressive Disorder
Eligibility:
All Genders
20-40 years
Brief Summary
As an important micro-ecological factor in human body, intestinal flora is closely related to the occurrence and development of major depressive disorder. The purpose of our study is to investigate a ...
Detailed Description
Participants (30 patients and 10 controls) will be recruited in the clinical psychological department of Beijing Chaoyang hospital. Patients with first-episode major depressive disorder confirmed by s...
Eligibility Criteria
Inclusion
- The proportion between male and female in each of groups was 1:1
- Han Chinese
- Permanent resident population of Beijing
- Body Mass Index,18.5-23.9
- Signed informed consent
Exclusion
- Other severe mental disease diagnosis
- Alcohol and other substance abuse or dependence
- Patients with contraindicated signs of duloxetine
- A history of clinically significant physical disorders, including any cardiovascular, liver, kidney, respiratory, blood, endocrine, and neurological disorders, as well as clinically significant laboratory abnormalities of unstable or expected therapeutic intervention during the study period
- The apparent risk of suicide and/or the patient is considered by the investigator to be at serious risk of suicide
- Patients who had received antibiotics, probiotics and hormones within one month
Key Trial Info
Start Date :
April 10 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 1 2023
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04347577
Start Date
April 10 2020
End Date
April 1 2023
Last Update
April 17 2020
Active Locations (1)
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1
Beijing Chao-Yang Hospital
Beijing, Beijing Municipality, China, 100020