Status:
TERMINATED
Awake Prone Positioning to Reduce Invasive VEntilation in COVID-19 Induced Acute Respiratory failurE
Lead Sponsor:
University College Hospital Galway
Conditions:
ARDS, Human
Mechanical Ventilation Complication
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Prone positioning (PP) is an effective first-line intervention to treat moderate-severe acute respiratory distress syndrome (ARDS) patients receiving invasive mechanical ventilation, as it improves ga...
Detailed Description
Prone positioning (PP) is an adjunctive therapy used that has been proven to save lives in sedated patients with confirmed moderate-severe acute respiratory distress syndrome (ARDS) receiving invasive...
Eligibility Criteria
Inclusion
- Suspected or confirmed COVID19 infection
- Bilateral Infiltrates on CXR
- SpO2 \<94% on FiO2 40% by either venturi facemask or high flow nasal cannula
- RR \<40
- Written informed consent
Exclusion
- Age \<18
- Uncooperative or likely to be unable to lie on abdomen for 16 hours
- Receiving comfort care only
- Multi-organ failure
- RR\>40
- Contraindication to PP (e.g. vomiting, abdominal wound, unstable pelvic/spinal lesions, pregnancy \>20/40 gestation, severe brain injury).
Key Trial Info
Start Date :
July 11 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 26 2021
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT04347941
Start Date
July 11 2020
End Date
January 26 2021
Last Update
December 2 2021
Active Locations (1)
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1
Galway University Hospital
Galway, Ireland