Status:
COMPLETED
IL-32 Isoforms Levels in GCF and Plasma of the Patients With Periodontitis
Lead Sponsor:
Bulent Ecevit University
Conditions:
Periodontitis
Eligibility:
All Genders
25-55 years
Brief Summary
Interleukin (IL)-32, which has been recently reported to be associated with periodontitis, has been suggested to have pleiotropic effect due to its 9 different isoforms. The aim of this study was to i...
Eligibility Criteria
Inclusion
- Have at least 20 natural teeth, excluding third molars.
- Periodontitis patients had at least two non-adjacent sites per quadrant with probing depth (PD) ≥ 5 mm and clinical attachment level (CAL) ≥ 5 mm with gingival inflammation, and alveolar bone loss affecting \>30% of the teeth, as detected on clinical and radiographical examinations.
- Periodontally healthy control group had no sign of gingival inflammation, no PD \> 3mm and no evidence of attachment or bone loss
Exclusion
- History of systemic disease.
- Regular use of any drugs which can effect the immune system or inflammatory response in the 6 months preceding the start of the study.
- Periodontal treatment during last 6 months that could affect periodontal status.
- Smoking.
- History of radiotherapy or chemotherapy.
- Current pregnancy, lactation or menopause.
Key Trial Info
Start Date :
October 1 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 1 2019
Estimated Enrollment :
54 Patients enrolled
Trial Details
Trial ID
NCT04350489
Start Date
October 1 2017
End Date
May 1 2019
Last Update
April 20 2020
Active Locations (1)
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1
Ordu University
Ordu, Turkey (Türkiye), 52100