Status:

COMPLETED

Biofreeze and the Effect on Knee Osteoarthritis

Lead Sponsor:

Memorial University of Newfoundland

Conditions:

Knee Osteoarthritis

Eligibility:

All Genders

50-80 years

Phase:

PHASE2

PHASE3

Brief Summary

Knee osteoarthritis (OA) is a progressive disease that can be accompanied by considerable joint pain and dysfunction. It is a goal in the medical field to find effective treatments for knee OA that ar...

Detailed Description

Knee osteoarthritis (OA) is a disease which results in deterioration with articular cartilage and bone tissue of the knee joint (Felson et al., 2000). The disease is prevalent in the elderly and as it...

Eligibility Criteria

Inclusion

  • Men and women aged 50-80 years
  • Body mass index (BMI) less than 40
  • Knee osteoarthritis of grade one or more according to Kellgren-Lawrence scale
  • Average pain intensity of grade 4 or more on a 10-point visual analogue scale for at least 6 months.
  • Meet clinical and radiographic criteria of the American College of Rheumatology (ACR) for knee OA

Exclusion

  • Acute arthritis,
  • Rheumatologic diseases
  • Infective arthritis
  • Traumatic arthritis,
  • History of knee replacement surgery
  • Patients receiving multiple corticosteroid injections (Greater than 2 injections)

Key Trial Info

Start Date :

November 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2024

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT04351594

Start Date

November 1 2020

End Date

January 1 2024

Last Update

December 4 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Memorial University, Faculty of Medicine Department of Surgery

St. John's, Newfoundland and Labrador, Canada, A1B3V6