Status:
COMPLETED
Immunological Profiling of Patients With COVID-19 in Respiratory Distress
Lead Sponsor:
Centre Hospitalier Universitaire de Nīmes
Collaborating Sponsors:
Institute of Human Genetics, Montpellier
Conditions:
SARS-CoV-2
Covid-19
Eligibility:
All Genders
18+ years
Brief Summary
The study investigators hypothesize that the pneumonia arising in patients with COVID-19 is largely of immunopathological origin. The investigators will therefore seek to define the immune activation ...
Detailed Description
SARS-CoV inhibits the viral detection systems and the signaling pathways of type I interferons (IFN-I). The weakness of the initial interferon response is predictive of the severity of future lung dis...
Eligibility Criteria
Inclusion
- The patient must be a member or beneficiary of a health insurance plan
- Patient hospitalized in respiratory resuscitation or in the service of Infectious and Tropical Diseases of the CHU de Nîmes with infection by SARS-CoV-2, confirmed by RT-PCR or by an antigen test.
Exclusion
- The subject is in a period of exclusion determined by a previous study
- The patient is under safeguard of justice
- Patient already under ventilation transferred from another center
Key Trial Info
Start Date :
April 9 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 12 2022
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT04351711
Start Date
April 9 2020
End Date
December 12 2022
Last Update
December 10 2025
Active Locations (1)
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1
CHU de Nimes
Nîmes, France