Status:

UNKNOWN

Observational Trial of the Longitudinal Effects of CFTR Modulator Drugs

Lead Sponsor:

National Jewish Health

Collaborating Sponsors:

Cystic Fibrosis Foundation

Conditions:

Cystic Fibrosis

Eligibility:

All Genders

18+ years

Brief Summary

CF patients enrolled in this protocol will be recruited from patients followed by the Adult CF Program at National Jewish Health. Patients will be selected based on planned use of a CFTR modulator by ...

Eligibility Criteria

Inclusion

  • Documented diagnosis of CF with an eligible mutation for modulator treatment.
  • Age 18 years old or older.
  • Patient is starting a CFTR modulator as part of their clinical care or switching CFTR modulator therapy agents, pending FDA approval.
  • Ability to perform reproducible Pulmonary Function Tests.
  • Willingness to comply with study procedure and willingness to provide written consent.

Exclusion

  • • Presence of a condition or abnormality that, in the opinion of the Principal Investigator (PI), would compromise the safety of the patient or the quality of the data.

Key Trial Info

Start Date :

September 16 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT04353752

Start Date

September 16 2019

End Date

December 1 2025

Last Update

September 30 2022

Active Locations (1)

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National Jewish Health

Denver, Colorado, United States, 80206