Status:

COMPLETED

Study Of Cabozantinib Treatment In Patients With Unresectable, Locally Advanced Or Metastatic Renal Cell Carcinoma Who Progressed After Previous Treatment With Checkpoint Inhibitors

Lead Sponsor:

Ipsen

Conditions:

Locally Advanced or Metastatic Renal Cell Carcinoma

Eligibility:

All Genders

18+ years

Brief Summary

To understand the epidemiology, treatment patterns and outcomes of patients with metastatic Renal Cell Carcinoma (mRCC). Data from mRCC patients who received cabozantinib versus non-cabozantinib Tyros...

Eligibility Criteria

Inclusion

  • Evidence of metastatic Renal Cell Carcinoma (mRCC) during the study period (May 01, 2016 to March 31, 2020);
  • Patients who received cabozantinib or non-cabozantinib TKI regimens during identification period (May 01, 2016 to September 30, 2019);
  • Patients who received CPIs, as monotherapy, or in combination with a cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) inhibitor (e.g. ipilimumab+nivolumab), as the latest treatment for mRCC administrated before cabozantinib or other TKI therapy;
  • Patients ≥ 18 years of age as of their index date
  • Patients who received care at a US Oncology Network site
  • Patients with ≥ 2 visits within the US Oncology Network.

Exclusion

  • Patients enrolled in a clinical trial at any time during index period
  • Patients receiving treatment for another documented primary cancer diagnoses during the study period

Key Trial Info

Start Date :

January 30 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 5 2020

Estimated Enrollment :

247 Patients enrolled

Trial Details

Trial ID

NCT04353765

Start Date

January 30 2020

End Date

June 5 2020

Last Update

November 17 2021

Active Locations (1)

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McKesson Life Sciences

The Woodlands, Texas, United States, 77380