Status:
COMPLETED
Protocols of IVF/ICSI in Poor Responders
Lead Sponsor:
Cairo University
Conditions:
Infertility, Female
Eligibility:
FEMALE
30-43 years
Phase:
PHASE3
Brief Summary
Comparing two ovarian induction protocols in poor responders in IVF/ICSI cycles
Detailed Description
The two groups of poor responders are randomized into either; a minimal dose stimulation protocol involving letrozole, recombinant FSH and GnRH antagonist versus a microflare conventional protocol wit...
Eligibility Criteria
Inclusion
- 1- More than 1 year of infertility 2 - Poor ovarian responder according to the Bologna criteria:
- Advanced maternal age
- Previous poor ovarian response
- Abnormal tests of ovarian reserve (AFC \< 5-7, AMH \<0.5-1.1 ng/ml)
Exclusion
- Age \> 43 years
- baseline FSH \>15 mIU/ml
- Previous ovarian surgery
- Ovarian endometrioma
- Uterine anomaly or myoma
- Any medical disorder
- Any hormonal disorder eg. hyperprolactinemia
- BMI \> 30 kg/m2
- Severe male factor
Key Trial Info
Start Date :
June 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 31 2021
Estimated Enrollment :
132 Patients enrolled
Trial Details
Trial ID
NCT04356105
Start Date
June 1 2020
End Date
October 31 2021
Last Update
November 16 2021
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
IVF centre, Obstetrics and Gynaecology Department, Cairo University Hospitals (Kasr EL Aini)
Cairo, Egypt, 12311
2
Cairo University
Cairo, Egypt