Status:
UNKNOWN
QUantitative Assessment of Swallowing After Radiation (QUASAR)
Lead Sponsor:
Loren Mell, MD
Conditions:
Head and Neck Cancer
Dysphagia
Eligibility:
All Genders
18+ years
Brief Summary
To use novel methods for quantitative analysis of VFSS (videofluoroscopic swallow study, also known as modified barium swallow) to study and compare dysphagia in patients treated for head and neck car...
Detailed Description
The QUASAR study will use a prospective, observational, cross sectional design (See Schema). HNC patients treated with definitive RT and immunotherapy or chemotherapy (cetuximab or cisplatin) will und...
Eligibility Criteria
Inclusion
- Biopsy-proven, un-resected invasive carcinoma of the head and neck.
- Treated with definitive RT and concurrent systemic therapy or treated within the past 4-24 months
- Concurrent systemic therapy with Cisplatin, Cetuximab or immunotherapy.
- Age ≥ 18
- Able to understand and willing to sign a written informed consent.
Exclusion
- Prior radiotherapy that would result in overlap of planned radiation therapy fields.
- Prior systemic chemotherapy, unless as part of the coordinated plan of care for the treatment of the carcinoma (e.g., induction/neoadjuvant chemotherapy is allowed)
- Planned adjuvant (i.e., following definitive chemoradiotherapy) chemotherapy or surgery
Key Trial Info
Start Date :
September 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2024
Estimated Enrollment :
42 Patients enrolled
Trial Details
Trial ID
NCT04359199
Start Date
September 1 2020
End Date
December 31 2024
Last Update
February 10 2023
Active Locations (2)
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1
UC San Diego Moores Cancer Center
La Jolla, California, United States, 92093
2
UCSD Moores Cancer Center
La Jolla, California, United States, 92093