Status:
UNKNOWN
The Role of Lipids in Immune Cell Function in SLE Patients
Lead Sponsor:
University College, London
Collaborating Sponsors:
University College London Hospitals
Conditions:
Lupus Erythematosus, Systemic
Eligibility:
All Genders
18-80 years
Brief Summary
The overall aim of this project is to investigate the different types of immune cells found in the blood of patients with Systemic Lupus Erythematosus (SLE) and healthy donors. We know that the amount...
Detailed Description
Accelerated atherosclerosis is a serious complication of autoimmunity including patients with both adult and juvenile onset systemic lupus erythematosus (SLE). This suggests that defects in fat levels...
Eligibility Criteria
Inclusion
- Diagnosis of SLE according to American College of Rheumatology revised criteria
- Having given written informed consent prior to undertaking any study-related procedures.
- Male and female patients between the ages of 18 and 80 years.
- Patients who have met all the above inclusion criteria listed and healthy donors will be screened for the following exclusion criteria:
Exclusion
- Under any administrative or legal supervision.
- Conditions/situations such as:
- A concomitant autoimmune disease
- Impossibility to meet specific protocol requirements (e.g. blood sampling).
- Patient is the Investigator or any sub-investigator, research assistant, pharmacist, study coordinator, other staff or relative thereof directly involved in the conduct of the protocol.
- Uncooperative or any condition that could make the patient potentially non-compliant to the study procedures.
- Pregnant or breast-feeding women, currently or in the last three months prior to inclusion.
- Patients who have been vaccinated in the last three months prior to inclusion.
Key Trial Info
Start Date :
February 15 2016
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 31 2020
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT04361734
Start Date
February 15 2016
End Date
August 31 2020
Last Update
April 24 2020
Active Locations (1)
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1
University College London Hospitals NHS Foundation Trust
London, United Kingdom, NW1 2BU