Status:
COMPLETED
Signal Propagation and Its Relationship to Cognitive Performance in the Aging Human Brain (Focus or Spread)
Lead Sponsor:
Insel Gruppe AG, University Hospital Bern
Conditions:
Healthy Aging
Eligibility:
All Genders
20-75 years
Phase:
NA
Brief Summary
In the next three decades, the world's population over 60 years old is expected to more than double its size. Even in the absence of an obvious pathology (i.e., healthy aging), advancing age is typica...
Eligibility Criteria
Inclusion
- Informed consent as documented by signature
- Age between 20-30 or 65-75 years
- Neurologically healthy, i.e., with no documented or present neurological disease or brain injury
- Normal or corrected-to-normal visual acuity
Exclusion
- Any instable medical condition, in particular epilepsy (past or present, including seizures or febrile convulsions)
- Any surgical intervention to the brain
- Heart diseases
- Implanted medical devices (e.g., cochlear implants, infusion pumps, neurostimulators, pacemakers)
- History of migraine or strong headaches
- Sleep deprivation
- Presence of non-MRI safe metal in the body
- Drug or alcohol abuse
- Intake of any medication that is likely to lower seizure threshold
- Claustrophobia
- For female participants: in order to participate in the study, female participants in reproductive age need to take a pregnancy test (a standard urine pregnancy test will be provided).
- For female participants: breastfeeding
- Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, etc. of the participant
- Lack of knowledge of the German language
- Participation in another study with investigational drug within the 30 days preceding and during the present study
- Previous enrolment into the current study
- Enrolment of the investigator, his/her family members, employees and other dependent persons
Key Trial Info
Start Date :
June 25 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 18 2021
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04361760
Start Date
June 25 2020
End Date
May 18 2021
Last Update
October 5 2021
Active Locations (1)
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1
Department of Neurology, Inselspital, Bern University Hospital
Bern, Switzerland, 3010