Status:
COMPLETED
Modulatory Effects of Deep Brain Stimulation on Cerebral Cortical Activity
Lead Sponsor:
The Cleveland Clinic
Collaborating Sponsors:
Farmer Foundation
Conditions:
DBS
Parkinson Disease
Eligibility:
All Genders
40-80 years
Phase:
NA
Brief Summary
The purpose of this study is to learn about how deep brain stimulation (DBS) affects brain activity in those with Parkinson's disease (PD) and essential tremor (ET). The effect of therapeutic and non-...
Detailed Description
Deep brain stimulation (DBS) is a standard-of-care, FDA approved therapy for Parkinson's disease (PD) and tremor and well over 1,000 patients have been implanted at the Cleveland Clinic in the past 20...
Eligibility Criteria
Inclusion
- between 40 and 80 years old
- ability to consent
- diagnosis of idiopathic Parkinson Disease or ET for a duration of at least 4 years
- implanted with DBS (STN, GPi or VIM) for at least 3 months
Exclusion
- secondary Parkinsonism, stroke, or progressive central nervous system disease other than Parkinson's disease or essential tremor
- cognitive impairment meeting criteria for dementia on formal neuropsychological evaluation
- lack of fluency in English which would invalidate cognitive testing
- current alcohol or substance abuse
- hearing or visual impairment precluding sensory or cognitive testing
Key Trial Info
Start Date :
January 31 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 10 2023
Estimated Enrollment :
66 Patients enrolled
Trial Details
Trial ID
NCT04361955
Start Date
January 31 2020
End Date
August 10 2023
Last Update
January 8 2024
Active Locations (1)
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1
Cleveland Clinic
Cleveland, Ohio, United States, 44195