Status:
COMPLETED
Improving Working Memory in Older Adults
Lead Sponsor:
Boston University Charles River Campus
Conditions:
Large-scale Physiological Foundations of Memory Decline in Aging Humans
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The research program will evaluate the theoretical claim that age-related memory and cognitive decline in humans result from the inefficient orchestration of rhythmic activity within large-scale corti...
Detailed Description
We hypothesize that aged-related memory and cognitive impairments emerge from large-scale functional dysconnectivity, and by stimulating the brain noninvasively with extremely weak levels of electrica...
Eligibility Criteria
Inclusion
- The following general inclusion criteria apply to all subjects: must be between the ages of 68-80 (except for Experiment 1 where subjects must be between the ages of 18-30), have normal or corrected-to-normal vision, color vision, nonpregnant, no metal implants in head, no implanted electronic devices, no history of neurological problems or head injury, no skin sensitivity, no claustrophobia, no dementia (normal Mini Mental State Examination between 24-30; Montreal Cognitive Assessment \> 25), no depression (normal Beck Depression Inventory II \<13; Geriatric Depression Scale \< 10), and cannot be taking any psychoactive medication.
Exclusion
Key Trial Info
Start Date :
September 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 30 2025
Estimated Enrollment :
964 Patients enrolled
Trial Details
Trial ID
NCT04362696
Start Date
September 1 2019
End Date
April 30 2025
Last Update
August 3 2025
Active Locations (1)
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1
677 Beacon St. Room 308
Boston, Massachusetts, United States, 02215