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Status:

COMPLETED

Investigation of the B- and T-cell Repertoire and Immune Response in Patients With Acute and Resolved COVID-19 Infection

Lead Sponsor:

National Cancer Institute (NCI)

Conditions:

COVID-19

Eligibility:

All Genders

18+ years

Brief Summary

Background: People who get infected with COVID-19 have an unpredictable risk to worsen and die. This makes it hard to decide who can quarantine at home and who should be treated at a hospital. Resear...

Detailed Description

Background: Patients infected with COVID-19 have an unpredictable risk to worsen and die, making it difficult to decide who can quarantine at home and who should be monitored for respiratory failure ...

Eligibility Criteria

Inclusion

  • INCLUSION CRITERIA:
  • Individuals who meet one of the following groups:
  • Patients with a confirmed or suspected diagnosis of COVID-19 infection, current or resolved; or,
  • Normal donors. Note: For the purpose of this study, normal donors are those without a known current, past, or suspected COVID-19 infection; individuals may have other medical comorbidities or conditions.
  • At least 18 years of age
  • Ability of patient or Legally Authorized Representative (LAR) to understand and the willingness to sign a written informed consent document
  • EXCLUSION CRITERIA: Individuals with COVID-19
  • \- Desire of the patient or normal donor not to submit samples, or medical contraindication to sending samples.
  • EXCLUSION CRITERIA: Normal Donors
  • \- No Exclusions

Exclusion

    Key Trial Info

    Start Date :

    April 27 2020

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    February 10 2025

    Estimated Enrollment :

    679 Patients enrolled

    Trial Details

    Trial ID

    NCT04362865

    Start Date

    April 27 2020

    End Date

    February 10 2025

    Last Update

    March 7 2025

    Active Locations (4)

    Enter a location and click search to find clinical trials sorted by distance.

    Page 1 of 1 (4 locations)

    1

    Medstar Washington Hospital Center

    Washington D.C., District of Columbia, United States, 20010

    2

    Medstar Franklin Square Medical Center

    Baltimore, Maryland, United States, 21237

    3

    National Institutes of Health Clinical Center

    Bethesda, Maryland, United States, 20892

    4

    Medstar Montgomery Medical Center

    Olney, Maryland, United States, 20832