Status:

TERMINATED

Chronic Fatigue Etiology and Recovery in Covid-19 Patients: the Role of Fatigability

Lead Sponsor:

Centre Hospitalier Universitaire de Saint Etienne

Collaborating Sponsors:

University of Saint-Etienne

Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques

Conditions:

Chronic Fatigue Syndrome

Intensive Care Unit

Eligibility:

All Genders

35-80 years

Phase:

NA

Brief Summary

Chronic fatigue is the most common and debilitating symptom in intensive care unit (ICU) survivors. Indeed, it has been widely reported that patients who stayed in ICU for prolonged periods report a f...

Eligibility Criteria

Inclusion

  • Inclusion Criteria for patients who have been in intensive care :
  • Diagnosed with Covid-19
  • Ventilated in ICU for at least 3 consecutive days
  • ICU discharge between 4 and 8 weeks
  • Approval received from a physician
  • Command of the French language
  • Inclusion Criteria for patients who have NOT been in intensive care :
  • Diagnosed with Covid-19 : positive serological test or positive PCR test following nasopharyngeal swabbing
  • Approval received from a physician
  • Command of the French language
  • Exclusion Criteria:
  • Taking neuroactive substances that can alter corticospinal excitability
  • Patients with co-morbidities leading to significant fatigue: e.g. cancerous pathologies, sleep apnea
  • Patients with neurodegenerative or neuromuscular disease
  • Contraindication to the application of a magnetic field
  • Contraindication to the practice of Magnetic Resonance Imaging
  • Participant is pregnant
  • Patients with psychiatric disorders
  • Paraplegic and hemiplegic patients
  • Addictive disorders

Exclusion

    Key Trial Info

    Start Date :

    May 27 2020

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    March 1 2022

    Estimated Enrollment :

    69 Patients enrolled

    Trial Details

    Trial ID

    NCT04363606

    Start Date

    May 27 2020

    End Date

    March 1 2022

    Last Update

    March 25 2025

    Active Locations (8)

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    Page 1 of 2 (8 locations)

    1

    CHU de Grenoble

    Grenoble, France

    2

    Clinique de la Sauvegarde - Lyon

    Lyon, France

    3

    Hôpital Croix Rousse - HCL

    Lyon, France

    4

    Centre Hospitalier de Lyon Sud

    Pierre-Bénite, France, 69310