Status:

WITHDRAWN

The LEAD COVID-19 Trial: Low-risk, Early Aspirin and Vitamin D to Reduce COVID-19 Hospitalizations

Lead Sponsor:

Louisiana State University Health Sciences Center in New Orleans

Conditions:

COVID

Vitamin D Deficiency

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

Although the novel SARS-CoV-2 virus (COVD-19) is classified as an acute respiratory infection, emerging data show that morbidity and mortality are driven by disseminated intravascular coagulopathy. Un...

Detailed Description

Although the novel SARS-CoV-2 virus (COVD-19) is classified as an acute respiratory infection, emerging data show that morbidity and mortality are driven by disseminated intravascular coagulopathy. Da...

Eligibility Criteria

Inclusion

  • Patients \> 18 years
  • Written informed consent
  • New (within 24 hours) COVID-19 diagnosis

Exclusion

  • Pregnant patients or Prisoners
  • History of GI bleeding or peptic ulcer disease, or spontaneous bleeding from other sites; History of thrombocytopenia; History of chronic kidney disease; Concurrent use of nonsteroidal anti-inflammatory drugs, or steroids.
  • Hypervitaminosis D and associated risk factors: Renal failure, Liver failure, Hyperparathyroidism, Sarcoidosis, Histoplasmosis

Key Trial Info

Start Date :

May 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2020

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT04363840

Start Date

May 1 2020

End Date

December 1 2020

Last Update

December 27 2021

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