Status:
RECRUITING
Interaction Between Host, Microenvironment and Immunity on Gastrointestinal Neoplasms
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Gastrointestinal Neoplasms
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The primary objective: association study of characteristics of tumoral microenvironment and immunity of digestive cancers with patients' overall survival (OS).
Detailed Description
The study aims to explore relationship between the molecular subgroups (DNA and RNA analysis), tumor microenvironment, host (immunity system, premetastatic niche, microbiota, metabolism) and survival ...
Eligibility Criteria
Inclusion
- Carcinoma of colorectal, pancreatic, biliary tract or gastro-oesophageal, or neuroendocrine digestive tumors with cytologically or histologically proven, regardless of the stage;
- Diagnosis between 1998 and 2030;
- Be \>/= 18 years;
- Have obtained signed informed consent (exemption for dead patients);
- Affiliated to the French social security - welfare system in France (CMU included).
Exclusion
- Patient under tutoraship or curatorship;
- Foreign patient under AME schema, a medical help from the state in France;
- Pregnant or breastfeeding women (for prospective study);
- Any clinical, psychological or social reason which should influence patient compliance with protocol, according to investigator;
- Patient refusal.
Key Trial Info
Start Date :
January 13 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2031
Estimated Enrollment :
6300 Patients enrolled
Trial Details
Trial ID
NCT04363983
Start Date
January 13 2021
End Date
January 1 2031
Last Update
February 23 2022
Active Locations (1)
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1
Digestive Surgery Department, Ambroise Paré Hospital, APHP
Boulogne-Billancourt, France, 92100