Status:
TERMINATED
Impact of a Intra-tracheal Intubation With Curarization or Without Curarization
Lead Sponsor:
Nantes University Hospital
Conditions:
Intubation Complication
Eligibility:
All Genders
18+ years
Brief Summary
VHIntubation is a French monocentric and observational study that will assess the impact of two intra-tracheal intubation preparation procedures (curarization versus remifentanil) on the voice, using ...
Detailed Description
Some surgeries are known to expose patients to voice disorders (thyroidectomy, parathyroidectomy, carotid surgery…). However, voice disorders can be due, among other things, to a laryngeal nerves alte...
Eligibility Criteria
Inclusion
- Patients included in " REMICRUSH " study
- patient's non-opposition to participation in research
- Inclusions criteria in REMICRUSH are :
- male or female aged from 18 to 80 years old
- surgery requiring general anaesthesia with tracheal with oro-tracheal intubation
- Rapid sequence intubation indication
- aspiration risk defined as : fasting \< 6h00, digestive occlusion, functional ileus, vomiting \< 12h00, orthopaedic trauma \< 12h00, severe gastric reflux, gastroparesis and/or dysautonomia and or gastro-oesophagus surgery
- signed informed consent sheet ; or emergency procedure if impossible
Exclusion
- Patients non-included in " REMICRUSH " study
- Patients with cervical surgery
- Patient declines to participate in research
- Exclusion criteria in REMICRUSH are :
- planned impossible intubation
- suspected/known allergy to neuromuscular blockade or remifentanil
- neuromuscular disease forbidding neuromuscular blockade use
- Prolonged neuromuscular block former episode
- Malignant hyperthermia former episode
- Pre-operative respiratory failure (spO2\< 95%)
- Pre-operative hemodynamic failure (use of vasopressor) cardiac arrest
- A woman of childbearing age who has an active pregnancy and/or clinical signs suggestive of an active pregnancy and/or does not have a contraceptive or contraceptive method and has had unprotected sex within 15 days of the last menstrual period.
- Patients under justice protection
- Use of etomidate for anesthetic induction
Key Trial Info
Start Date :
June 16 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 31 2020
Estimated Enrollment :
7 Patients enrolled
Trial Details
Trial ID
NCT04364633
Start Date
June 16 2020
End Date
December 31 2020
Last Update
April 19 2022
Active Locations (1)
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1
Nantes University Hospital
Nantes, France, 44093