Status:

UNKNOWN

Antenatal and Intrapartum Risk Factors Associated With Neonatal Hypoxic Ischemic Encephalopathy

Lead Sponsor:

Assiut University

Conditions:

Neonatal Hypoxic Ischemic Encephalopathy

Eligibility:

All Genders

24-28 years

Brief Summary

Perinatal asphyxia is a major cause of hypoxic Ischemic encephalopathy (HIE), perinatal death and long term neurodisability. This can be devastating for the individual and their family; the healthcare...

Detailed Description

Antenatal, perinatal and postpartum data will be documented from the medical notes and from parental reports including; * Booking factors (maternal age, smoking, parity, previous lower segment caesar...

Eligibility Criteria

Inclusion

  • Clinical signs of neonatal encephalopathy(e.g. irritability, decreased responsiveness, coma, seizures, hypotonia, abnormal primitive reflexes, apnea, feeding disturbance, and abnormal cry), NICU admission, full-term infant with poor condition at birth (5-minute Apgar score \<7) and/or need for major resuscitation.

Exclusion

  • Preterm infant, full term infants with birth asphyxia but with congenital malformations or chromosomal abnormalities, infant of diabetic mother and CNS infections are excluded from the study.

Key Trial Info

Start Date :

September 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2022

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04364932

Start Date

September 1 2021

End Date

December 1 2022

Last Update

April 28 2020

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