Status:

RECRUITING

BUBOLight®, a New Phototherapy Device for the Treatment of the Newborn's Jaundice

Lead Sponsor:

University Hospital, Lille

Collaborating Sponsors:

Institut National de la Santé Et de la Recherche Médicale, France

Conditions:

Neonatal Jaundice

Eligibility:

All Genders

Up to 30 years

Phase:

NA

Brief Summary

About 50% of full-term newborns and 80% of premature infants develop jaundice which is due to hyperbilirubinemia. In the majority of cases, jaundice disappears naturally without treatment within three...

Eligibility Criteria

Inclusion

  • At time of birth, infant is \> 35 weeks gestation
  • Presence of jaundice confirmed by measurement of bilirubin (transcutaneous bilirubinometer)
  • Total bilirubinemia rate requiring phototherapy according to National Institute for Health and Clinical Excellence.
  • Weight ≥2.500kg
  • Judged in good health by the investigator following the clinical examination and the medical data (absence of perinatal asphyxia, antibiotic treatment, respiratory disorders)
  • Absence of fœto-maternal rhesus incompatibility or Kell

Exclusion

  • Newborn already treated with phototherapy
  • Febrile state with body temperature \> 37.8°C
  • Total bilirubinaemia level is equal or excess 100 μmol / L of the indication of phototherapy.
  • Patient whose jaundice is due to haemolysis, obstruction functional or anatomical.
  • Minor relative
  • Newborn requiring exchange transfusion
  • Newborn with congenital erythropoietic porphyria or a family history of porphyria.
  • Patient requiring treatment other than phototherapy

Key Trial Info

Start Date :

October 8 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2026

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT04365998

Start Date

October 8 2020

End Date

December 1 2026

Last Update

December 23 2025

Active Locations (1)

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1

Hop Jeanne de Flandre Chu Lille

Lille, France, 59037