Status:
COMPLETED
Norepinephrine for Hypotension in Cesarean Section
Lead Sponsor:
Assiut University
Conditions:
Hypotension
Cesarean Section
Eligibility:
FEMALE
18-45 years
Phase:
NA
Brief Summary
Hypotension is a very common consequence of the sympathetic vasomotor block caused by spinal anesthesia for cesarean section. Maternal symptoms such as nausea, vomiting and dyspnea frequently accompan...
Detailed Description
Phenylephrine has a potent direct α effect, with virtually no β effects at clinical doses, however when given at higher than required doses, it may induce baroreceptor-mediated bradycardia with a cons...
Eligibility Criteria
Inclusion
- Patients who fall in category 2 and 3 according to the classification of Caesarean section made by Royal College of Obstetrician and Gynaecologists.
Exclusion
- Patient refusal either to study enrollment or to spinal anesthesia.
- Any absolute contraindication to spinal anesthesia e.g. coagulopathy, skin infection at site of injection.
- Allergy to any of study drugs.
- Patients with cardiac morbidities, hypertensive disorders or peripartum bleeding
- BMI \> 40 kg/m²
- Baseline systolic blood pressure \< 100 mmHg.
Key Trial Info
Start Date :
April 10 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 4 2022
Estimated Enrollment :
180 Patients enrolled
Trial Details
Trial ID
NCT04367103
Start Date
April 10 2021
End Date
May 4 2022
Last Update
January 4 2023
Active Locations (1)
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1
Assiut University
Asyut, Egypt, 71515