Status:
COMPLETED
Ultrasonography for Fluid Assessment in Parturients With Preeclampsia Undergoing Cesarean Section
Lead Sponsor:
Mansoura University
Conditions:
Elective Cesarean Section
Preeclampsia
Eligibility:
FEMALE
19-45 years
Brief Summary
Preeclampsia is a multifocal syndrome reported in 2-8 % of pregnancies. It is diagnosed in the second half of pregnancy by two separate measurements of systolic blood pressure ≥140 mmHg and/or a diast...
Detailed Description
Fluid resuscitation is a key determinant in the management of these parturients. Hypovolemia exacerbates organ failure, whereas volume overload results in pulmonary edema. In this setting, the use of ...
Eligibility Criteria
Inclusion
- Singleton pregnancy.
- 32 - 41 weeks gestational age.
- Preeclampsia: Blood Pressure ≥140/90 mmHg after 20 weeks' gestation and proteinuria ≥300 mg/24 hours or 1+ on urine dipstick
- Elective cesarean delivery under spinal anesthesia.
Exclusion
- Body mass index (BMI) ≥40 kg/m2.
- Significant cardiovascular disease
- Other obstetrical problems
- Other uteroplacental problems
- Abruption placenta.
- Already treated for acute lung pathology prior to enrollment.
- Contraindications to spinal anesthesia.
- INR \>1.5 or PLT\<100,000 /mm3.
- Women presenting in labor.
- Previous thoracic surgery.
- Previous ocular surgery
- Ocular trauma
- Glaucoma.
- Preoperative pulmonary disease:
- Increased serum creatinine level ≥1.1 mg/dL.
Key Trial Info
Start Date :
June 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2021
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04370847
Start Date
June 1 2020
End Date
December 1 2021
Last Update
November 13 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Mansoura University
Al Mansurah, DK, Egypt, 050