Status:
COMPLETED
WeanINg From Mechanical Ventilation for ARDS CovId-19 Patients Guided by Combined Thoracic UltraSound.
Lead Sponsor:
University Hospital, Toulouse
Conditions:
COVID-19
ARDS, Human
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The most feared complication of COVID-19 infection is the occurrence of an acute respiratory distress syndrome (ARDS) that requires ICU admission and prolonged mechanical ventilation in more than 2% o...
Detailed Description
Identifying patients at risk for postextubation distress using standard clinical criteria and the only available test the investigators have, that is, the spontaneous breathing trial (SBT) remains a c...
Eligibility Criteria
Inclusion
- ICU admission for severe acute respiratory distress syndrome (ARDS, as previously defined5 by a ratio of the partial pressure of arterial oxygen to the fraction of inspired oxygen of less than 150) related to COVID-19.
- Non paralyzed because of neuromuscular blocking agents.
- Ventilated patient in pressure support mode for at least 6 hours and at most 24 hours.
- Surrogate decision maker's consent.
- Affiliated person or beneficiary of a social security scheme.
Exclusion
- Reduction or cessation of active treatment.
- Paraplegia with medullar level more than T8.
- Tracheostomy before hospital admission.
- History of severe respiratory illness.
- Patient under juridical protection.
- Pregnancy or nursing woman.
- Enrolled in another trial evaluating mechanical ventilation.
Key Trial Info
Start Date :
April 22 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2022
Estimated Enrollment :
89 Patients enrolled
Trial Details
Trial ID
NCT04372680
Start Date
April 22 2020
End Date
April 1 2022
Last Update
October 17 2023
Active Locations (2)
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1
CHU de LIMOGES
Limoges, France
2
CHU de TOULOUSE
Toulouse, France, 31000