Status:
COMPLETED
Human Ab Response & immunoMONItoring of COVID-19 Patients
Lead Sponsor:
Rennes University Hospital
Conditions:
SARS-CoV-2 Coronavirus
Acute Respiratory Distress Syndrome
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Prospective, mono centric study on COVID-19 patients with or without acute respiratory distress syndrome (ARDS) to analyse the dynamics of the immune response and to search for biomarkers of evolution
Detailed Description
Assessed by World Health Organisation as a pandemic on March 11, COVID-19 is caused by the SARS-CoV-2 coronavirus. The spectrum of its clinical manifestations is strikingly broad and extends from mild...
Eligibility Criteria
Inclusion
- Patient older than 18 years old
- Patients COVID-19 :
- hospitalized for less than 48 hours in intensive care unit (ICU) with ARDS (PaO2/Fi02 \< 200) or
- hospitalized with respiratory syndrome without need of invasive mechanical ventilation
- Patients hospitalized for less than 48 hours in intensive care unit (ICU) with ARDS (PaO2/Fi02 \< 200) from other causes
- Patients who have given their consent or included in an emergency situation
- Patients affiliated to medical care insurance
Exclusion
- Pregnant women
- Preexisting immune disorders (HIV-infection, malignancy, graft, treatment with immunosuppressive agents)
- Patients legally protected (under judicial protection, guardianship), persons deprived of liberty
Key Trial Info
Start Date :
May 25 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 9 2021
Estimated Enrollment :
71 Patients enrolled
Trial Details
Trial ID
NCT04373200
Start Date
May 25 2020
End Date
March 9 2021
Last Update
May 23 2023
Active Locations (1)
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1
CHU Rennes
Rennes, France, 35033