Status:

UNKNOWN

Effect of Simvastatin as Pulpotomy Agent in Cariously Exposed Permanent Molars

Lead Sponsor:

Postgraduate Institute of Dental Sciences Rohtak

Conditions:

Reversible Pulpitis

Eligibility:

All Genders

15-40 years

Phase:

NA

Brief Summary

The study will compare the outcome of complete pulpotomy in mature permanent mandibular molars with deep carious lesions by using Mineral Trioxide Aggregate and Simvastatin -alpha tricalcium phosphate...

Detailed Description

After a thorough history, clinical and radiographic examination with all eligibility confirmation, written informed consent will be taken from the patient after explaining the procedure, its associate...

Eligibility Criteria

Inclusion

  • Patient willing to participate in the study.
  • Age group of 15 to 40 years
  • Mature permanent mandibular molars with reversible pulpitis (positive response on the cold test and early response as compared to the adjacent or contralateral tooth)
  • Teeth exhibiting occlusal pulp exposure from primary dental caries.
  • Absence of periapical lesions assessed by radiographic examination.
  • Tooth demonstrating no mobility or swelling and no tenderness to percussion or palpation

Exclusion

  • Primary teeth.
  • Teeth with irreversible pulpitis (spontaneous pain) or pulp necrosis, chronic periodontitis, cracked tooth, internal or external resorption, calcified canals, associated with sinus tract and furcation or apical radiolucency.
  • Immune-compromised, pregnant and patients with any systemic disorder.
  • Patients taking statin medication.
  • Failure to obtain authorization from the patient.

Key Trial Info

Start Date :

December 1 2018

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 30 2020

Estimated Enrollment :

56 Patients enrolled

Trial Details

Trial ID

NCT04374214

Start Date

December 1 2018

End Date

June 30 2020

Last Update

May 5 2020

Active Locations (1)

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PGIDS

Rohtak, Haryana, India, 124001