Status:

UNKNOWN

Fruit and Vegetable Intervention in Lactating Women to Reduce Breast Cancer Risk

Lead Sponsor:

University of Massachusetts, Amherst

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Breast Cancer Female

Inflammation

Eligibility:

FEMALE

18+ years

Phase:

NA

Brief Summary

Mechanistic data show that compounds in fruits and vegetables have anti-inflammatory and anti-carcinogenic properties that can reduce breast cancer risk. However, observational and interventional stud...

Detailed Description

Overview of home visits and activities completed by all participants Visit 1 Introductory Visit (1.5 hours) 24-Hour Dietary Recalls completed during the week (1-2 hours) Occurs at 5 weeks postpartum ...

Eligibility Criteria

Inclusion

  • Have given birth in past five weeks or are currently pregnant
  • Breastfeeding baby at entry into the study
  • Consuming five or fewer servings of fruits and vegetables daily at baseline
  • Live within 25 miles of Amherst MA

Exclusion

  • Invasive breast cancer
  • Any cancer except non-melanoma skin cancer in past five years
  • History of Crohn's disease, celiac sprue, or other malabsorption syndrome, which may interfere with digesting or absorption of nutrients
  • A personal history of diabetes (excluding gestational diabetes)
  • Baseline BMI of \<18.5
  • Dietary restrictions that prevent participant from eating 8 to 10 servings of fruits and vegetables

Key Trial Info

Start Date :

October 24 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 1 2024

Estimated Enrollment :

400 Patients enrolled

Trial Details

Trial ID

NCT04374747

Start Date

October 24 2019

End Date

April 1 2024

Last Update

November 4 2022

Active Locations (1)

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1

University of Massachusetts Amherst

Amherst, Massachusetts, United States, 01003