Status:

RECRUITING

Heparin vs Placebo for Cardiac Catheterization

Lead Sponsor:

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Conditions:

Cardiac Disease

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

Patients undergoing cardiac catheterization will be randomized to 3 groups: no anticoagulant, low dose anticoagulant and high dose anticoagulant.

Detailed Description

Patients undergoing diagnostic cardiac catheterization via the trans-radial approach will be randomly allocated (1:1:1) to receive either low-dose UFH (25 IU/Kg -maximal dose 3,000 IU), high-dose UFH ...

Eligibility Criteria

Inclusion

  • diagnostic cardiac catheterization; Small size sheath; patency of the ulno-palmar circulation

Exclusion

  • abnormal ulno-palmar circulation; Prior radial artery thrombosis; Prior surgery close to the access site; Emergent cardiac catheterization; History of HIT or allergy to heparin; Patients requiring anticoagulation

Key Trial Info

Start Date :

October 5 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2026

Estimated Enrollment :

3600 Patients enrolled

Trial Details

Trial ID

NCT04374799

Start Date

October 5 2020

End Date

December 1 2026

Last Update

August 24 2025

Active Locations (2)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 1 (2 locations)

1

Hamilton Health Sciences

Hamilton, Ontario, Canada

2

London Health Sciences Centre

London, Ontario, Canada, N6A5A5