Status:

RECRUITING

Resting Full-cycle Flow Ratio (RFR) Versus Angiography to Guide Revascularization Strategy in Patients Undergoing Coronary Artery By-pass Grafting (CABG)

Lead Sponsor:

Diagram B.V.

Conditions:

Coronary Artery Disease

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Different trials have shown that fractional flow reserve (FFR) could successfully guide revascularization in patients undergoing percutaneous coronary intervention (PCI). It is conceivable that a sim...

Eligibility Criteria

Inclusion

  • All patients between 18 or older undergoing CABG
  • Patients willing and capable to provide written informed consent

Exclusion

  • Previous CABG
  • Concomitant severe valvular disease intervention
  • Remaining (expected) coronary stenosis of \> 50% diameter stenosis distally to graft anastomosis
  • Left ventricular ejection fraction \<30%
  • Known transmural myocardial infarction
  • Documented microvascular disease
  • RFR/FFR measurement judged impossible
  • Life expectancy \<2 years
  • Participation in other investigational clinical trials

Key Trial Info

Start Date :

February 3 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 30 2027

Estimated Enrollment :

500 Patients enrolled

Trial Details

Trial ID

NCT04375306

Start Date

February 3 2020

End Date

June 30 2027

Last Update

February 1 2024

Active Locations (4)

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Page 1 of 1 (4 locations)

1

Imelda ziekenhuis

Bonheiden, Belgium

2

AZ Sint-Jan Brugge

Bruges, Belgium

3

Medical University of Silesia

Katowice, Poland

4

SUSCCH

Banská Bystrica, Slovakia