Status:
COMPLETED
Atorvastatin Effect on Contrast Induced Nephropathy in Diabetic Patients Undergoing Elective Coronary Intervention
Lead Sponsor:
Mohamed Abdelfatah
Conditions:
Coronary Disease
Eligibility:
All Genders
30-80 years
Phase:
PHASE4
Brief Summary
Investigate of the potential benefit of acute pretreatment with high dose atorvastatin (80 mg) in reduction of the incidence of CIN in diabetic patients indicated for elective coronary intervention.
Detailed Description
The study is a prospective, multi-center, randomized, placebo-controlled study. The ethical committee of the Faculty of Medicine, Assiut University approved the study protocol. 200 diabetic patients ...
Eligibility Criteria
Inclusion
- 200 diabetic patients with indication for coronary intervention participated in the study
Exclusion
- Current statin treatment within the previous three months.
- Chronic renal failure patients on renal dialysis, or serum creatinine more than 1.5 mg/dl.
- Severe co-morbidities i.e. patients with cancer, advanced liver cirrhosis.
- Contraindications to statin therapy.
- Contrast media injection within the preceding 10 days.
- Pregnancy.
- Refusal of consent.
Key Trial Info
Start Date :
March 15 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 2 2020
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04375787
Start Date
March 15 2020
End Date
June 2 2020
Last Update
February 16 2022
Active Locations (1)
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1
Assiut University
Asyut, Egypt, 71515