Status:
COMPLETED
Diets Enriched With Pecans
Lead Sponsor:
University of Georgia
Collaborating Sponsors:
Georgia Pecan Commission
Conditions:
Hypercholesterolemia
Obesity
Eligibility:
All Genders
30-75 years
Phase:
NA
Brief Summary
Background: Previous studies report that daily pecan consumption reduces cholesterol in healthy adults while promoting weight maintenance. Purpose: To examine the impact of daily pecan consumption wi...
Detailed Description
This was a single-blind, randomized controlled trial. The investigators recruited subjects with hypercholesterolemia (high blood cholesterol levels) or at higher risk for cardiovascular disease (CVD) ...
Eligibility Criteria
Inclusion
- Ages 30-75y with higher cholesterol levels or BMI of 28 kg/m2 or greater (A higher cholesterol level is indicated by "Borderline High/Undesirable" in two or more of the variables (total cholesterol 200-239 mg/dL, LDL cholesterol 130-159 mg/dL, triglycerides 150-199 mg/dL) or "High" in either total cholesterol (240 mg/dL and higher) or LDL (160 mg/dL or higher).
Exclusion
- Familial hypercholesterolemia (individuals with LDL levels greater than the 95th percentile or HDL levels lower than the 20th percentile based on age and sex)
- Nut consumption \>2 servings/week or tree nut butter consumption \>3 servings/week
- Hormone replacement therapy \<5 years
- Women who are pregnant or planning to become pregnant
- Regular exercise of \>3 hours/week
- Weight gain or loss of \>5% of body weight during last 3 months
- Plans to begin a weight loss/exercise regiment
- History of medical or surgical events that could affect digestion or swallowing
- Gastrointestinal surgeries, conditions or disorders
- Chronic or metabolic diseases
- Atherosclerosis, previous myocardial infarction, stroke, cancer
- Fasting blood glucose levels \>126 mg/dl
- Blood pressure \>180/120 mmHg
- Medication use that affects digestion, absorption, metabolism
- Lipid-lowering medications
- Medications for diabetes or attention deficit disorders (with or without hyperactivity)
- Steroid/hormone therapies
- Individuals on medically prescribed or special diet
- Individuals with food allergies to foods specifically in the study
- Individuals taking fish oil supplements
- Excessive alcohol consumption (greater than 3 drinks/d for men; greater than 2 drinks/d for women)
- Tobacco or nicotine use
Key Trial Info
Start Date :
August 10 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2021
Estimated Enrollment :
124 Patients enrolled
Trial Details
Trial ID
NCT04376632
Start Date
August 10 2018
End Date
June 1 2021
Last Update
June 1 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Georgia- Department of Foods and Nutrition
Athens, Georgia, United States, 30605