Status:
RECRUITING
Liver Transplant Combined With Neoadjuvant Chemo-radiotherapy in the Treatment of Unresectable Hilar Cholangiocarcinoma. A Prospective Multicenter Study.
Lead Sponsor:
Hospital Vall d'Hebron
Conditions:
Unresectable Cholangiocarcinoma
Eligibility:
All Genders
18-70 years
Brief Summary
A prospective multicentre study which includes patients ≤ 70 years-old diagnosed of unresectable hilar cholangiocarcinoma (hCCA) ≤3cm in radial diameter, without evidence of lymph node or distant meta...
Detailed Description
A prospective multicentre pilot study which includes patients ≤ 70 years-old diagnosed of unresectable hilar cholangiocarcinoma (hCCA) ≤3cm in radial diameter, without evidence of lymph node or distan...
Eligibility Criteria
Inclusion
- Willing and able to provide written consent form
- Age ≤ 70 years-old
- ECOG 0 or 1
- Unresectable hCCA ≤3cm in radial diameter
Exclusion
- Those patients who have received chemotherapy or radiotherapy previously out of protocol
- Liver, extrahepatic or lymph node metastases
- Previous intent of surgical resection or percutaneous biopsy
- Previous or concurrent cancer that is different in primary site or histology from adenocarcinoma, except cervical carcinoma in situ, localized prostate cancer, treated basal cell carcinoma, superficial bladder tumors (Ta, Tis, T1). Any cancer curatively treated 5 years prior to entry is permitted.
- Infection no controlled
Key Trial Info
Start Date :
April 24 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2027
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT04378023
Start Date
April 24 2020
End Date
June 1 2027
Last Update
September 9 2025
Active Locations (1)
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1
Department of HPB Surgery and Transplants, Hospital Vall d´Hebron
Barcelona, Spain, 08035