Status:
COMPLETED
Epigenetics of Post-exertional Malaise in Patients With ME/CFS
Lead Sponsor:
Vrije Universiteit Brussel
Conditions:
Fatigue Syndrome, Chronic
Eligibility:
FEMALE
18-70 years
Phase:
NA
Brief Summary
Exploring epigenetic mechanisms of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) is crucial to understand the mechanisms underlying its pathophysiology. Three potential candidates have...
Detailed Description
The only way to improve the diagnosis and treatment of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) is to better understand the mechanisms underlying its pathophysiology. Central nerv...
Eligibility Criteria
Inclusion
- diagnosis of ME/CFS established by a MD experienced in the field of internal medicine and ME/CFS - according to the published international criteria developed by the Canadian Consensus Criteria (CCC);
- age between 18 and 70 years old;
- body mass index (BMI) below 30 (no obesity).
Exclusion
- presence of other neurological disorders (Parkinson's disease, Multiple Sclerosis, etc);
- presence of systemic disorders (lupus erythematosus, rheumatoid arthritis, etc.);
- presence or history of cardiac disorders (coronary heart disease, history of heart failure, etc);
- presence or history of cancer;
- presence or history of neuropathic pain (e.g. pain related to herpes zoster virus);
- pregnancy;
Key Trial Info
Start Date :
April 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 30 2023
Estimated Enrollment :
105 Patients enrolled
Trial Details
Trial ID
NCT04378634
Start Date
April 1 2021
End Date
April 30 2023
Last Update
November 7 2023
Active Locations (1)
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1
UZ Brussel
Brussels, Belgium, 1090