Status:
COMPLETED
Anti-inflammatory Effect of Curcumin, Homotaurine, Vitamin D3 on Human Vitreous in Patients With Diabetic Retinopathy
Lead Sponsor:
University of Molise
Collaborating Sponsors:
Humanitas Gradenigo - Torino
Cliniche Humanitas Gavazzeni
Conditions:
Diabetic Retinopathy
Eligibility:
All Genders
18-80 years
Brief Summary
Dosage of pro-inflammatory cytokines and soluble mediators (TNFα, IL6, IL2 and PDGF-AB) performed on 25 vitreous biopsies taken from patients with diabetic retinopathy and treated with increasing dose...
Detailed Description
Diabetic retinopathy is one of the most common complications of diabetes mellitus and is a leading cause of vision loss and blindness in the working-age population worldwide. DR is being recognized as...
Eligibility Criteria
Inclusion
- age ≥18 years
- patients with diabetic retinopathy requiring vitrectomy
- willingness to participate in the study following its indications
Exclusion
- previous vitrectomy in the study eye
- previous buckle surgery in the study eye
- previous intravitreal injection in the study eye
- concurrent retinovascular or other ocular inflammatory disease
- history of ocular trauma
- concomitant intake of any topical or systemic NSAID or corticosteroid therapy
- presence of systemic inflammations
Key Trial Info
Start Date :
September 16 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 2 2019
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT04378972
Start Date
September 16 2019
End Date
December 2 2019
Last Update
May 7 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Molise
Campobasso, Italy