Status:

UNKNOWN

Interest of Tracheal Extubation in Positive Pressure on Postoperative Oxygenation in Adult Digestive Surgery: Prospective Randomized Study ExPress

Lead Sponsor:

University Hospital, Rouen

Conditions:

Patients Undergoing Digestive Surgery With Orotracheal Intubation

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

Evaluation of a postoperative tracheal extubation protocol under positive pressure in accordance with international recommendations. Two arms: the first with "classic" extubation with disconnection o...

Eligibility Criteria

Inclusion

  • Age\> 18 and \<80
  • Patient going to benefit from general anesthesia with orotracheal intubation for surgery lasting more than 60 minutes at the visceral surgery unit of the Rouen University Hospital.
  • Person affiliated to a social security scheme
  • Person who has read and understood the newsletter and signed the consent form

Exclusion

  • Minor patients or age\> 80 years
  • History of Obstructive Sleep Apnea Syndrome
  • Chronic respiratory failure / History of chronic obstructive pulmonary disease
  • Surgery \< 60 minutes
  • Use of methylene blue intraoperatively
  • Extubation finally performed in the operating room
  • orotracheal intubation difficult to induce general anesthesia
  • Suspected inhalation during orotracheal intubation
  • Pneumothorax per operative
  • Heart failure authenticated by trans thoracic ultrasound \<50%
  • Neuromuscular pathologies (myasthenia gravis, myopathies)
  • Body mass index\> 35
  • Emergency surgery
  • Patient with an ASA IV score (ie according to the definition of the American Society of Anesthesiology)
  • Major surgical complications (hemorrhagic shock)
  • Major anesthetic complications (anaphylactic shock, bronchospasm)
  • Pregnant or parturient or lactating woman or woman of childbearing age without proven contraception
  • Person deprived of their liberty by an administrative or judicial decision or person placed under the protection of justice / guardianship or curatorship

Key Trial Info

Start Date :

June 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 1 2022

Estimated Enrollment :

208 Patients enrolled

Trial Details

Trial ID

NCT04381949

Start Date

June 1 2020

End Date

June 1 2022

Last Update

May 11 2020

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