Status:
UNKNOWN
Effects of NMES in Critically Ill Patients
Lead Sponsor:
Escola Superior de Ciencias da Saude
Conditions:
Mechanical Ventilation Complication
Muscle Weakness Condition
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Muscle wasting occurred early and rapidly in critically ill patients. Early therapeutic strategies to either maintain muscle structure and function should be encouraged. Neuromuscular electrical stimu...
Detailed Description
Patients with prolonged mechanical ventilation require deep sedation and mechanical ventilation, factors predisposing to the development of skeletal muscle wasting and acute muscle atrophy. Strategies...
Eligibility Criteria
Inclusion
- Aged 18 years or older
- Intubated and expected to remain invasively mechanically ventilated the day after tomorrow
- laboratory confirmed COVID-19 (diagnosis of SARS-CoV-2 via reverse transcriptase polymerase chain reaction as per the World Health Organization protocol or by nucleic acid based isothermal amplification)
Exclusion
- Dependent for activities of daily living in the month prior to current ICU admission (gait aids are acceptable).
- Documented cognitive impairment.
- Proven or suspected spinal cord injury or other neuromuscular disease that will result in permanent or prolonged weakness (not including ICU acquired weakness)
- Death is deemed inevitable as a result of the current illness and either the patient or treating clinical or substitute decision maker are not committed to full active treatment
- pregnancy
- patients with unstable fractures in the vertebral column and lower limbs.
Key Trial Info
Start Date :
February 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2021
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT04382378
Start Date
February 1 2021
End Date
December 31 2021
Last Update
March 15 2021
Active Locations (1)
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1
Secretaria de Saúde do Distrito Federal
Brasília, Federal District, Brazil, 700000