Status:
UNKNOWN
Inhaled Ibuprofen to Treat COVID-19
Lead Sponsor:
Química Luar SRL
Collaborating Sponsors:
National Council of Scientific and Technical Research, Argentina
Centro de Excelencia en Productos y Procesos Córdoba
Conditions:
Coronavirus Infection
Respiratory Disease
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The study aims to evaluate the reduction in severity and progression of lung injury with inhaled ibuprofen in patients with severe acute respiratory syndrome due to SARS-CoV-2 virus.
Eligibility Criteria
Inclusion
- Provision of written informed consent by the patient OR by the patient's Legal Representative.
- Confirmed or suspected SARS-CoV-2 infection;
- Pneumonia without criteria of severity.
- With some of the following conditions:
- Diabetes.
- Cardiovascular disease.
- Chronic kidney disease.
- Chronic obstructive pulmonary disease.
- Structural diseases of the lung
- Immunocompromise.
- Patient who presents negative results by rtPCR for SARS CoV-2, in case of being highly suspicious, the patient may receive it empirically until the results are obtained.
- No unstable bronchial asthma
Exclusion
- The doctor considers that participation in the Program is not the best for patients or for any condition that prevents the Program from being followed safely.
- Patients with a history of unstable bronchial asthma
- The patient is allergic to ibuprofen or any of the compounds in the preparation.
- Hypersensitivity to the drug, nasal polyps syndrome, angioedema or bronchospasm against aspirin or other NSAIDs.
- Pregnant or lactating woman, or positive pregnancy test on a pre-dose exam.
- Patient who is expected to be transferred to another place other than the place where the Program starts, within 7 days of starting it.
Key Trial Info
Start Date :
May 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2021
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04382768
Start Date
May 1 2020
End Date
January 1 2021
Last Update
June 11 2020
Active Locations (1)
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1
Centro de Excelencia en Productos y Procesos Córdoba
Córdoba, Argentina, 5000