Status:

COMPLETED

iTransition Development

Lead Sponsor:

Emory University

Collaborating Sponsors:

National Institute of Mental Health (NIMH)

Conditions:

Human Immunodeficiency Virus

HIV Seropositivity

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Youth living with HIV are at high risk of falling out of care when they transition from pediatric to adult care. The investigators are proposing to develop a mobile app to help both clinical providers...

Detailed Description

The transition from pediatric/adolescent to adult-oriented care settings can be disruptive to care engagement for youth living with HIV (YLH). The objective of this trial is to pilot and evaluate eff...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • For YLH Historical Control Group
  • YLH (regardless of gender/assigned sex at birth) age ≥ 18 years;
  • Has plan for HCT within next 6 months;
  • Enrolled in care at Grady IDP pediatric/adolescent clinic or CHOP AI/SI clinics.
  • For YLH iTransition Intervention Group
  • YLH (regardless of gender/assigned sex at birth) age ≥ 18 years;
  • Has plan for HCT within next 6 months;
  • Enrolled in care at Grady IDP pediatric/adolescent clinic or CHOP AI/SI clinics;
  • Owns a smartphone and/or tablet
  • Reports consistent internet access (defined as no lapse \>24 hours in last 6 months) via their smartphone or tablet.
  • For Provider Group
  • Staff member at Grady IDP (pediatric/adolescent clinic, adult women's clinic, and/or adult men's clinic), CHOP AI/SI clinics, UPHS: HUP or Presby infectious disease clinics;
  • Works with transitioning YLH;
  • Access to internet via any device (e.g., smartphone, tablet, computer);
  • Endorse participation in the HCT process.
  • For Transition Champion Group
  • Staff member at Grady IDP (pediatric/adolescent clinic, adult women's clinic, and/or adult men's clinic), CHOP AI/SI clinics, UPHS: HUP or Presby infectious disease clinics;
  • Works with transitioning YLH;
  • Endorse participation in the HCT process;
  • Access to internet via any device (e.g., smartphone, tablet, computer);
  • Nominated by clinic staff where employed to be iTransition intervention point person (champion).
  • Exclusion Criteria For YLH Historical Control Group
  • Youth who are \<18 years old;
  • Youth who are not living with HIV;
  • Transition is not expected (from pediatric/adolescent to adult care) within the next 6 months;
  • Presence of serious psychiatric symptoms (e.g., active hallucinations, thought disorder) that would impair the individual's ability to provide true informed consent or participate in the study activities;
  • Visibly distraught (e.g., suicidal, homicidal, exhibiting violent behavior) at the time of consent.
  • For YLH iTransition Intervention Group
  • Youth who are \<18 years old;
  • Youth who are not living with HIV;
  • Transition is not expected (from pediatric to adult care) within the next 6 months;
  • Does not own smartphone/tablet and has inconsistent internet access (i.e. has had one or more lapse \>24 hrs in the last three months);
  • Presence of serious psychiatric symptoms (e.g., active hallucinations, thought disorder) that would impair the individual's ability to provide true informed consent or participate in the study activities;
  • Visibly distraught (e.g., suicidal, homicidal, exhibiting violent behavior) at the time of consent.
  • For Provider Group
  • Not a staff member at Grady IDP, CHOP SI/AI, UPHS: HUP or Presby infectious disease clinics;
  • Does not work with transitioning YLH;
  • Does not have access to internet via any device (e.g., smartphone, tablet, computer).
  • For Transition Champion Group
  • Not a staff member at Grady IDP, CHOP SI/AI, UPHS: HUP or Presby infectious disease clinics;
  • Does not work with transitioning YLH;
  • Does not have access to internet via any device (e.g., smartphone, tablet, computer).

Exclusion

    Key Trial Info

    Start Date :

    August 28 2020

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    June 30 2024

    Estimated Enrollment :

    78 Patients enrolled

    Trial Details

    Trial ID

    NCT04383223

    Start Date

    August 28 2020

    End Date

    June 30 2024

    Last Update

    August 13 2025

    Active Locations (3)

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    Page 1 of 1 (3 locations)

    1

    Grady Hospital

    Atlanta, Georgia, United States, 30303

    2

    Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, United States, 19104

    3

    University of Pennsylvania Health System - HUP and Presby infectious disease clinics

    Philadelphia, Pennsylvania, United States, 19104

    iTransition Development | DecenTrialz