Status:

COMPLETED

Combined Corneal Wavefront-guided TPRK and ACXL Following ICRS Implantation in Management of Moderate Keratoconus

Lead Sponsor:

Shaaban Elwan

Conditions:

Keratoconus

Eligibility:

All Genders

20-48 years

Phase:

NA

Brief Summary

Background: Keratoconus leads to gradual progressive loss of vision in young and adult patients. For visual rehabilitation and to hinder keratoconus progressionthe investigators designed this study to...

Detailed Description

Patients and Methods: This study conducted upon 36 eyes of 36 patients with moderate keratoconus who undergoing combined corneal wavefront-guided TPRK and accelerated corneal CXL at least 3 months af...

Eligibility Criteria

Inclusion

  • Adult patient with age \> 20 years old and intolerant to contact lense use
  • patients had moderate keratoconus (45-54 D in both meridians) without corneal scarring
  • Central pachymetry ≥ 400 μm and if progression had been noted over the previous 6 months.

Exclusion

  • Patients with central or paracentral corneal scarring
  • Central pachymetry \<400 μm, systemic autoimmune disease
  • History of herpetic keratitis, pregnancy, lactation, or severe dry eye syndrome.

Key Trial Info

Start Date :

October 1 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 30 2020

Estimated Enrollment :

36 Patients enrolled

Trial Details

Trial ID

NCT04383301

Start Date

October 1 2018

End Date

April 30 2020

Last Update

May 13 2020

Active Locations (1)

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1

Security forces hospital

Riyadh, Central, Saudi Arabia, 11481-3643