Status:

COMPLETED

Trial to Compare Two Strains of BCG

Lead Sponsor:

Bandim Health Project

Collaborating Sponsors:

University of Southern Denmark

Conditions:

Death, Infant

Morbidity;Infant

Eligibility:

All Genders

Up to 42 years

Phase:

PHASE4

Brief Summary

The trial will be a two-year outcome assessor-blinded RCT at the maternity ward of hospital Simão Mendes (HNSM) in urban Bissau, Guinea-Bissau to compare BCG-Japan versus BCG-Russia 1:1 in 15,000 infa...

Detailed Description

This two-year outcome assessor-blinded RCT will be conducted at the maternity ward of hospital Simão Mendes (HNSM) in urban Bissau, Guinea-Bissau to compare BCG-Japan versus BCG-Russia 1:1 in 15,000 i...

Eligibility Criteria

Inclusion

  • Healthy infants present at the HNSM maternity ward on the day of discharge or procuring vaccination at the ward.

Exclusion

  • Infants older than 6 weeks (\>42 days) of age
  • Infants that have already received either BCG or oral polio vaccine (OPV)
  • Infants that are moribund due to gross malformation or acute illness (about to die or be transferred to the pediatric ward according to the local health physician assessment; the latter children may be recruited when they are discharged from the pediatric ward or the neonatal intensive care unit).

Key Trial Info

Start Date :

May 4 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2022

Estimated Enrollment :

16390 Patients enrolled

Trial Details

Trial ID

NCT04383925

Start Date

May 4 2020

End Date

December 1 2022

Last Update

January 22 2024

Active Locations (1)

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Bandim Health Project

Bissau, Guinea-Bissau