Status:

UNKNOWN

The Safety and Effectiveness of Tocilizumab in Rheumatoid Arthritis

Lead Sponsor:

Peking Union Medical College Hospital

Conditions:

Arthritis, Rheumatoid

Eligibility:

All Genders

18-100 years

Brief Summary

The aim of this study is to investigate the safety and effectiveness of tocilizumab (Actemra®) using Chinese Rheumatology Information Platform (CRIP) on Chinese Rheumatology Data Centre (CRDC, http://...

Detailed Description

Tocilizumab (Actemra®) is a humanized monoclonal antibody targeting the human IL-6 receptor, which inhibits the binding of this cytokine to its receptor. It is the first monoclonal antibody developed ...

Eligibility Criteria

Inclusion

  • Patients at least 18 years of age.
  • Patients with a diagnosis of RA according to the revised (2010) ACR criteria.
  • Patients per treating physician's judgment to treat with Tocilizumab.
  • Signed written informed consent

Exclusion

  • Patients are receiving or have received any investigational agent 4 weeks (or 5 half-lives of investigational agent, whichever is longer) prior to enrollment of this study.
  • Subjects with contra-indications to Tocilizumab therapy as detailed in the label (with known hypersensitivity to Tocilizumab or accessories; or with active infections.).

Key Trial Info

Start Date :

December 27 2018

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 31 2022

Estimated Enrollment :

2500 Patients enrolled

Trial Details

Trial ID

NCT04384068

Start Date

December 27 2018

End Date

January 31 2022

Last Update

May 12 2020

Active Locations (1)

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Peking Union Medical College Hospital

Beijing, Beijing Municipality, China, 100005