Status:

COMPLETED

Role of Inflammasomes in COVID-19 Disease

Lead Sponsor:

Centre Hospitalier Universitaire de Nice

Conditions:

COVID-19 by SARS-CoV-2 Infection

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

As of March 25, 2020, 414,179 cases and 18,440 deaths secondary to Coronavirus 2019 disease (COVID-19) have been reported worldwide. The unfavorable course of the patients is characterized on the immu...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Age above 18 years old. SARS-CoV-2 infection confirmed by RT PCR or by serology Hospitalised patients with less than 14 days of COVID-19 symptoms. Date of first symptom being defined as to the date of one of the following symptoms : cough, dyspnea, fever above 38 °C, anosmia, dysgeusia or ageusia, chilblain Lupus erythematous Women of fertile age using at least one contraceptive method Health insurance Written informed consent
  • Exclusion criteria
  • Pregnant or breastfeeding female
  • Human immunodeficiency virus infection with CD4 under 200 cell/mm3
  • Aplasia
  • at-risk patients (minor, patient under judicial protection or tutorship)

Exclusion

    Key Trial Info

    Start Date :

    May 11 2020

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    December 30 2022

    Estimated Enrollment :

    99 Patients enrolled

    Trial Details

    Trial ID

    NCT04385017

    Start Date

    May 11 2020

    End Date

    December 30 2022

    Last Update

    March 22 2023

    Active Locations (2)

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    Page 1 of 1 (2 locations)

    1

    Ch Cannes, Réanimation

    Cannes, Alpes Maritimes, France, 06

    2

    CHU de nice

    Nice, Alpes-Maritimes, France, 06200