Status:

UNKNOWN

FSH Followed by HMG vs FSH Plus HMG in IVF

Lead Sponsor:

Mansoura University

Conditions:

IVF

Eligibility:

FEMALE

20-37 years

Phase:

PHASE4

Brief Summary

The aim of this study is to compare the clinical outcomes of sequential administration of FSH and HP-hMG FSH alone versus concomitant administration of FSH and HP-hMG during controlled ovarian stimula...

Detailed Description

Women who are planned to be subjected to IVF/ICSI through COS by long GnRHa protocol will be assessed for possibility of participation in our study. Eligible participants in our study will be those wi...

Eligibility Criteria

Inclusion

  • Women who are planned to be subjected to IVF/ICSI through COS by long GnRHa protocol.
  • Women with regular menstrual cycle (21-35 days) and normal uterine anatomy (confirmed by transvaginal ultrasound examination and in some cases hysteronsalpingography and hysteroscopy).

Exclusion

  • Age \< 20 or \> 37 years.
  • Body mass index (BMI) \< 18 or \> 30 kg/m2.
  • Low ovarian reserve (AFC \< 7 and/or AMH \< 1.1 ng/ml).
  • Presence of polycystic ovarian syndrome (PCOS).
  • Endometrioma or hydrosalpinx.
  • History of chemotherapy, radiotherapy or ovarian surgery.
  • The husband needs testicular biopsy to obtain sperm.
  • Previous implantation failure.

Key Trial Info

Start Date :

June 30 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 31 2022

Estimated Enrollment :

530 Patients enrolled

Trial Details

Trial ID

NCT04385342

Start Date

June 30 2020

End Date

August 31 2022

Last Update

June 9 2020

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Fertility Care Unit (FCU) in Mansoura University Hospital

Al Mansurah, Dakahlia Governorate, Egypt, 35111

2

Department of Obstetrics and Gynecology

Alexandria, Egypt

3

RAHEM Fertility Centre

Zagazig, Egypt