Status:
COMPLETED
LVN- IUS Versus Oral Megesterol Acetate in Treatment of Atypical Endometrial Hyperplasia
Lead Sponsor:
Zagazig University
Conditions:
Atypical Endometrial Hyperplasia
Eligibility:
FEMALE
Phase:
PHASE2
PHASE3
Brief Summary
This randomized controlled trial is aimed to compare the efficacy between Megestrol acetate (MA) and the levonorgestrel intrauterine system (LNG-IUD) regarding the ability and duration to produce comp...
Detailed Description
Up to 25% of cases with endometrial cancer and atypical hyperplasia occur in premenopausal women. The progressively increasing trend of delay in first conception increases such patients who wish to ha...
Eligibility Criteria
Inclusion
- All cases with evidence of atypical endometrial hyperplasia declining doing hysterectomy
Exclusion
- Cases with evidence of associated endometrial cancer.
- Cases with simple hyperplasia without atypia.
- Patients failed to collect at least 2 endometrial samples during treatment course.
Key Trial Info
Start Date :
May 20 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 25 2022
Estimated Enrollment :
143 Patients enrolled
Trial Details
Trial ID
NCT04385667
Start Date
May 20 2020
End Date
December 25 2022
Last Update
January 3 2023
Active Locations (1)
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1
Zagazig University
Zagazig, Sharqia Province, Egypt, 44511