Status:
COMPLETED
Measurement of Airway Opening Pressure (AOP) in Patients With Acute Respiratory Distress Syndrom and With or Without Covid 19.
Lead Sponsor:
University Hospital, Bordeaux
Conditions:
Acute Respiratory Distress Syndrome
Eligibility:
All Genders
18+ years
Brief Summary
Mechanical ventilation in ARDS requires protective ventilation and PEEP. Airway closer has to be overcome to reduce lung heterogeneity, AOP is measured globally with a ventilator PV curve without PEEP...
Detailed Description
Scientific justification: In one third of Acute Respiratory Distress Syndrome (ARDS), tidal inflation starts when an airway opening pressure (AOP) is overcome 1. This phenomenon of airway closure has...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- \- Patients hospitalized in the ICU and who suffered moderate to severe ARDS (Berlin criteria) equipped EIT over the age of 18.
- Exclusion criteria:
- Broncho-pleural leaks
- ECMO
- Pregnant or breastfeeding woman.
- Guardianship or curatorship
- Deprived of liberty
- No health insurance
- Impossibility to correctly position the EIT belt (e.g., dressings, chest drainage, etc.)
- Contra indications to EIT (e.g., implantable cardiac defibrillator, pacemaker, instable spinal lesions)
Exclusion
Key Trial Info
Start Date :
May 25 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 25 2022
Estimated Enrollment :
26 Patients enrolled
Trial Details
Trial ID
NCT04386720
Start Date
May 25 2020
End Date
May 25 2022
Last Update
August 29 2022
Active Locations (1)
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1
HOPITAL HAUT-LEVEQUE - Service Réanimation thoracique
Pessac, France, 33604