Status:
UNKNOWN
Incidence of Diabetes and Metabolic Disorders After TIPS in Cirrhotic Patients
Lead Sponsor:
University Hospital, Toulouse
Conditions:
Cirrhosis Portal
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Decompensated cirrhosis is associated with sarcopenia. TIPS is an efficient treatment of portal hypertension. Based on our retrospective data, TIPS induces in 30% of cirrhotic patients metabolic disor...
Detailed Description
Based on our retrospective data, we expect that one-third of cirrhotic patients develop glucose dysregulation after TIPS. A better knowledge of the metabolic disorders related to the TIPS could allow ...
Eligibility Criteria
Inclusion
- patient cirrhosis and portal hypertension justifying a treatment with TIPS
- written consent.
Exclusion
- contraindication for TIPS
- indications of TIPS in emergency or as part of the preparation for a surgical procedure,
- hepatocellular carcinoma outside Milan criteria or cancer at a palliative stage,
- a contra-indication to the realization of an OGTT,
- a hyperglycemic treatment (corticosteroids, somatostatin, etc.),
- hemoglobin \<7 g / dl,
- patients who have had a liver transplant,
- those for whom the follow-up is considered impossible or the vital prognosis is engaged in the short term,
- pregnant or lactating women,
- those unable to receive enlightened information,
- those participating in interventional research
- and finally the persons placed under safeguard of justice, tutelage or curatorship.
Key Trial Info
Start Date :
June 16 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 16 2022
Estimated Enrollment :
111 Patients enrolled
Trial Details
Trial ID
NCT04387058
Start Date
June 16 2019
End Date
June 16 2022
Last Update
May 13 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
CHU de Toulouse
Toulouse, Haute-garonne, France, 31000