Status:

COMPLETED

A Study to Assess the Effect of Cannabidiol Oil on Pain After Ureteroscopy for Kidney Stones

Lead Sponsor:

Mayo Clinic

Conditions:

Urinary Stone

Eligibility:

All Genders

18-75 years

Phase:

PHASE2

PHASE3

Brief Summary

The purpose of this study is to determine if CBD oil has any effect on decreasing postoperative pain control following ureteroscopy for urinary stone disease, and to determine if CBD oil has any effec...

Eligibility Criteria

Inclusion

  • Patients who are diagnosed with kidney or ureteral stones confirmed on imaging (CT of the abdomen and pelvis) and who elect for definitive treatment via ureteroscopy at two sites within a tertiary care institution.
  • Age 18-75 years of age.
  • Patients of either gender.
  • Patients of all ethnic backgrounds.
  • Capable of giving informed consent.
  • Capable and willing to fulfill the requirements of the study.

Exclusion

  • History of chronic pain.
  • Chronic use of opioid or other pain medication (\> 12 weeks).
  • Known allergy to CBD oil or other cannabinoids.
  • Known or suspected pregnancy.
  • Inability to give informed consent or unable to meet requirements of the study for any reason.
  • Bilateral ureteroscopy.
  • Current marijuana, cannabidiol (CBD), or dronabinol use.
  • Liver disease/cirrhosis.
  • Current treatment of seizures with clobazam, valproate, or other antiepileptic medications.

Key Trial Info

Start Date :

February 15 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 31 2022

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT04387617

Start Date

February 15 2021

End Date

January 31 2022

Last Update

January 18 2023

Active Locations (1)

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Mayo Clinic in Arizona

Phoenix, Arizona, United States, 85054