Status:
COMPLETED
Dornase Alfa Administered to Patients With COVID-19 (DACOVID)
Lead Sponsor:
Feinstein Institute for Medical Research
Collaborating Sponsors:
Cold Spring Harbor Laboratory
Conditions:
COVID-19
Mechanical Ventilation
Eligibility:
All Genders
18-85 years
Brief Summary
Mechanically ventilated patients with coronavirus disease 2019 (COVID-19) have a mortality of 24-53%, in part due to distal mucopurulent secretions interfering with ventilation. Dornase alfa is recomb...
Detailed Description
Demographic, clinical data, and outcomes were collected from the electronic medical records of five mechanically ventilated patients with COVID-19-including three requiring veno-venous extracorporeal ...
Eligibility Criteria
Inclusion
- mechanically ventilated patients with COVID-19
Exclusion
- healthy, non-ventilated
Key Trial Info
Start Date :
March 31 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 4 2020
Estimated Enrollment :
5 Patients enrolled
Trial Details
Trial ID
NCT04387786
Start Date
March 31 2020
End Date
September 4 2020
Last Update
November 13 2020
Active Locations (1)
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1
Feinstein Insitute for Medical Research at Northwell Health
Manhasset, New York, United States, 11030