Status:
COMPLETED
Traditional Chinese Medicine for the Treatment of Perennial Allergic Rhinitis on Gut Microbiota and Immune-modulation
Lead Sponsor:
Chang Gung Memorial Hospital
Conditions:
Allergic Rhinitis
Eligibility:
All Genders
20-60 years
Phase:
NA
Brief Summary
40 allergic rhinitis patients in the acute phase will be enrolled in the study. All the allergic patients should be confirmed those who are over 20 years old and hypersensitive to house dust mite alle...
Detailed Description
Perennial allergic rhinitis is an important disease in traditional Chinese medicine (TCM) due to its high prevalence rate in Taiwan. In our previous studies, a new mixed formula of Chinese herbs was e...
Eligibility Criteria
Inclusion
- Volunteer for study enrollment and sign inform consent
- Mite allergy confirmed by MAST test
- Over 20 years old
- Will have their blood collected twice and stool samples
- Allergic rhinitis patients in the acute phase will be treated with mixed formula of Chinese medicine for one months
Exclusion
- Women who are pregnant or breast-feeding
- Under treatment of western medicine including steroid, antihistamine, leukotriene inhibitor, immunosuppressant or stop above medication less than one month
- Under acute inflammatory disease such as pneumonia, sinusitis, bronchitis and so on vasomotor type allergic rhinitis
- History of allergy or adverse effect to Chinese herbs, poor compliance of herbal medicine severe organ function impairment, such as heart failure, liver failure, renal failure (eGFR \<60 mL/min/1.73 m2)
Key Trial Info
Start Date :
September 3 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 31 2021
Estimated Enrollment :
33 Patients enrolled
Trial Details
Trial ID
NCT04388358
Start Date
September 3 2019
End Date
January 31 2021
Last Update
February 9 2021
Active Locations (1)
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1
Chang Gung Memorial Hospital
Taoyuan District, Taiwan