Status:

UNKNOWN

A Cone Beam Computed Tomographic Evaluation of Healing of Apicomarginal Defects Using Autologous Platelet Aggregates

Lead Sponsor:

Postgraduate Institute of Dental Sciences Rohtak

Conditions:

Chronic Apical Periodontitis

Eligibility:

All Genders

18-55 years

Phase:

NA

Brief Summary

This study will evaluate the effect of PRF (platelet rich fibrin) on the healing of apicomarginal defects. Healing of the defects will be assessed 2 dimensionaly by periapical radiograph and 3 dimensi...

Detailed Description

Patients with apicomarginal defects as per the inclusion criteria will be randomly divided into two groups - (1) Test group - The denuded root surface will be covered by PRF (Choukron's method) and (2...

Eligibility Criteria

Inclusion

  • A negative response to vitality tests with radiographic evidence of periapical radiolucency with no general medical contraindications for oral surgical procedures.
  • Apicomarginal communication having probing depth \> 6mm.
  • Patients with no general medical contraindications for oral surgical procedures.
  • Recurrent episodes of purulent discharge.
  • Failed previous root canal treatment.
  • Failed previous surgery with persistent bony lesion.
  • Adequate final restoration with no clinical evidence of coronal leakage.

Exclusion

  • Clinical or radiographic evidence of root fracture.
  • Resorptive processes involving more than apical third of the root.
  • Any systemic disease contraindicating oral surgery including uncontrolled diabetes and pregnancy.
  • Any condition effecting rate of healing like smoking.

Key Trial Info

Start Date :

July 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2021

Estimated Enrollment :

32 Patients enrolled

Trial Details

Trial ID

NCT04389346

Start Date

July 1 2019

End Date

March 1 2021

Last Update

May 19 2020

Active Locations (1)

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1

Ankita Ramani

Rohtak, Haryana, India, 124001